TERMIUM Plus®
The Government of Canada’s terminology and linguistic data bank.
ONCOGENICITE [2 records]
Record 1 - internal organization data 2004-02-16
Record 1, English
Record 1, Subject field(s)
- Cancers and Oncology
- Environmental Studies and Analyses
- Toxicology
Record 1, Main entry term, English
- oncogenicity
1, record 1, English, oncogenicity
correct
Record 1, Abbreviations, English
Record 1, Synonyms, English
Record 1, Textual support, English
Record number: 1, Textual support number: 1 DEF
The ability of a substance to produce either benign or malignant tumors. 1, record 1, English, - oncogenicity
Record number: 1, Textual support number: 1 OBS
Do not confuse with "carcinogenicity," (q.v.), which refers to the power, ability or tendency to produce malignant tumors. 2, record 1, English, - oncogenicity
Record 1, French
Record 1, Domaine(s)
- Cancers et oncologie
- Études et analyses environnementales
- Toxicologie
Record 1, Main entry term, French
- oncogénicité
1, record 1, French, oncog%C3%A9nicit%C3%A9
correct, feminine noun
Record 1, Abbreviations, French
Record 1, Synonyms, French
- pouvoir oncogène 2, record 1, French, pouvoir%20oncog%C3%A8ne
correct, masculine noun
Record 1, Textual support, French
Record number: 1, Textual support number: 1 CONT
Une étude d'oncogénicité de 2 ans chez le rat a montré une augmentation de l'incidence chez la femelle des néoplasmes hépatiques et des polypes utérins et chez le mâle des adénomes thyroïdiens à la dose élevée de 25 mg/kg/jour. La dose sans effet tumorigène (5mg/kg/jour) détermine une exposition sanguine 25 fois supérieure à l'exposition humaine. Un étude d'oncogénicité à 2 ans chez la souris a entraîné une induction de tumeurs ovariennes bénignes à toutes les doses. 3, record 1, French, - oncog%C3%A9nicit%C3%A9
Record number: 1, Textual support number: 1 OBS
Ne pas confondre avec le terme «cancérogénicité» (voir cette fiche), qui ne s'emploie que pour désigner la propriété d'une substance qui peut provoquer ou favoriser l'apparition de tumeurs malignes seulement. 4, record 1, French, - oncog%C3%A9nicit%C3%A9
Record 1, Spanish
Record 1, Campo(s) temático(s)
- Tipos de cáncer y oncología
- Estudios y análisis del medio ambiente
- Toxicología
Record 1, Main entry term, Spanish
- oncogenicidad
1, record 1, Spanish, oncogenicidad
correct, masculine noun
Record 1, Abbreviations, Spanish
Record 1, Synonyms, Spanish
Record 1, Textual support, Spanish
Record number: 1, Textual support number: 1 DEF
La propiedad de producir tumores (no necesariamente cancerosos) en los animales o en el hombre. 1, record 1, Spanish, - oncogenicidad
Record 2 - internal organization data 2002-01-08
Record 2, English
Record 2, Subject field(s)
- Cytology
Record 2, Main entry term, English
- oncogenicity
1, record 2, English, oncogenicity
correct
Record 2, Abbreviations, English
Record 2, Synonyms, English
Record 2, Textual support, English
Record number: 2, Textual support number: 1 CONT
The primary interest of this laboratory is in the mechanism of cell transformation and oncogenicity of receptor protein tyrosine kinases (RPTKs). Currently, we are studying the ros oncogene, originally discovered in an avian sarcoma virus, human insulin receptor (IR) and human insulin-like growth factor I receptor (IGFR). Molecular basis for the oncogenic activation as well as signalling transduction pathways responsible for normal and oncogenic functions of those receptor PTKs are being explored. Regulation and intervention of those oncogenic RPTKs by potential suppressor "anti-oncogene" such as protein tyrosine phosphatase (PTPase) and dominant-negative mutants of downstream signalling molecules are being inquired. Finally, potential role of those and other RPTKs in the development and progression of human malignancy, particularly breast cancer, are also being examined. 1, record 2, English, - oncogenicity
Record 2, French
Record 2, Domaine(s)
- Cytologie
Record 2, Main entry term, French
- oncogénicité
1, record 2, French, oncog%C3%A9nicit%C3%A9
correct, feminine noun
Record 2, Abbreviations, French
Record 2, Synonyms, French
- tumorigénicité 2, record 2, French, tumorig%C3%A9nicit%C3%A9
correct, feminine noun
Record 2, Textual support, French
Record number: 2, Textual support number: 1 CONT
[...] les cellules utilisées doivent être soumises à des épreuves de tumorigénicité [...]. Bien que les techniques biochimiques permettent un dosage assez précis de la quantité d'ADN dans le produit fini, une mesure indépendante de la tumorigénicité potentielle doit être également fournie. 3, record 2, French, - oncog%C3%A9nicit%C3%A9
Record 2, Spanish
Record 2, Textual support, Spanish
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