TERMIUM Plus^®

Record 1,  Textual support,  English

Record number: 1, Textual support number: 1 DEF

A protein produced by macrophages in response to bacterial infection ...  4, record 1, English, - tumour%20necrosis%20factor

Record number: 1, Textual support number: 1 CONT

Tumor necrosis factor(TNF) was originally discovered as a serum protein with necrotizing effects on certain transplantable mouse tumors in vivo and cytotoxic effects against some transformed cells in vitro. The TNF family consists of two proteins designated TNF-alpha, also called cachectin, and TNF-beta, also called lymphotoxin, which are pleiotropic cytokines that can mediate a wide variety of biological effects. TNF-beta is produced by activated lymphocytes, whereas TNF-alpha is mostly produced by activated macrophages.  5, record 1, English, - tumour%20necrosis%20factor

Record number: 1, Textual support number: 1 OBS

A form made by genetic engineering is used in [some treatments].  4, record 1, English, - tumour%20necrosis%20factor

Record number: 1, Textual support number: 2 OBS

In specialized works, the term «tumour necrosis factor» often makes reference to the tumour necrosis factor alpha.  6, record 1, English, - tumour%20necrosis%20factor

Record 1,  Textual support,  French

Record number: 1, Textual support number: 1 CONT

Au cours des dernières années, on a mis en évidence un nombre croissant de protéines intervenant dans l'inflammation et l'immunité comme la croissance et l'inhibition cellulaires. Ces protéines, auxquelles on a donné le nom général de cytokines, comprennent […] le TNF […]  4, record 1, French, - facteur%20de%20n%C3%A9crose%20tumorale

Record number: 1, Textual support number: 1 OBS

[…] on connaît actuellement la séquence du TNF de plusieurs espèces et on le fabrique par génie génétique.  4, record 1, French, - facteur%20de%20n%C3%A9crose%20tumorale

Record number: 1, Textual support number: 2 OBS

Dans les ouvrages spécialisés, le terme «facteur de nécrose tumorale» fait souvent référence au facteur de nécrose tumorale alpha.  7, record 1, French, - facteur%20de%20n%C3%A9crose%20tumorale

Record 1,  Textual support,  Spanish

Record number: 1, Textual support number: 1 DEF

Polipéptido que interviene en los mecanismos reguladores inmunológicos, eliminando o inhibiendo el crecimiento de ciertas células tumorales.  1, record 1, Spanish, - factor%20de%20necrosis%20tumoral

Record number: 1, Textual support number: 1 OBS

Sustancia producida por los macrófagos que tiene la capacidad de destruir células cancerígenas.  2, record 1, Spanish, - factor%20de%20necrosis%20tumoral

Record 2,  Textual support,  English

Record number: 2, Textual support number: 1 DEF

A protein that is released by activated macrophages as an immune system defense and, when the defense is overwhelmed, is a cause of cachexia or toxic shock ...  5, record 2, English, - tumour%20necrosis%20factor%20alpha

Record number: 2, Textual support number: 1 OBS

In some specialized works, the term «tumour necrosis factor» makes reference to the tumour necrosis factor alpha.  6, record 2, English, - tumour%20necrosis%20factor%20alpha

Record number: 2, Textual support number: 2 OBS

TNF-a: "a" refers to the Greek letter alpha.  6, record 2, English, - tumour%20necrosis%20factor%20alpha

Record 2,  Textual support,  French

Record number: 2, Textual support number: 1 CONT

Les facteurs nécrosant les tumeurs font partie des cytokines. Il en existe deux : le TNF alpha (également appelé cachectine, pour son rôle dans la cachexie liée aux maladies inflammatoires chroniques), produit par de nombreux types de cellules immunitaires (monocytes, lymphocytes), et le TNF bêta […]  5, record 2, French, - facteur%20de%20n%C3%A9crose%20tumorale%20alpha

Record number: 2, Textual support number: 1 OBS

Dans certains ouvrages spécialisés, le terme «facteur de nécrose tumorale» fait référence au facteur de nécrose tumorale alpha.  7, record 2, French, - facteur%20de%20n%C3%A9crose%20tumorale%20alpha

Record number: 2, Textual support number: 2 OBS

TNF a : La lettre «a» représente la lettre grecque.  7, record 2, French, - facteur%20de%20n%C3%A9crose%20tumorale%20alpha

Record 2,  Textual support,  Spanish

Record 3,  Textual support,  English

Record number: 3, Textual support number: 1 DEF

The ratio of the oxygen transfer coefficient in mixed liquor to the oxygen transfer coefficient in clean water.  1, record 3, English, - alpha%20factor

Record number: 3, Textual support number: 1 OBS

In an activated sludge plant.  1, record 3, English, - alpha%20factor

Record number: 3, Textual support number: 2 OBS

alpha factor : term and definition standardized by ISO.  2, record 3, English, - alpha%20factor

Record 3,  Textual support,  French

Record number: 3, Textual support number: 1 DEF

Rapport du coefficient de transfert d'oxygène dans la liqueur mixte au coefficient de transfert d'oxygène dans de l'eau propre.  1, record 3, French, - facteur%20alpha

Record number: 3, Textual support number: 1 OBS

Pour une station par boues activées.  1, record 3, French, - facteur%20alpha

Record number: 3, Textual support number: 2 OBS

facteur alpha : terme et définition normalisés par l'ISO.  2, record 3, French, - facteur%20alpha

Record 3,  Textual support,  Spanish

Record number: 3, Textual support number: 1 DEF

Relación entre el coeficiente de transferencia de oxígeno en el licor mezclado y el coeficiente de transferencia de oxígeno en agua limpia.  1, record 3, Spanish, - factor%20alfa

Record number: 3, Textual support number: 1 OBS

En una planta de lodos activados.  1, record 3, Spanish, - factor%20alfa

Record 4,  Textual support,  English

Record number: 4, Textual support number: 1 CONT

The protein called EGF-R sets off the chain reaction that activates the mucous gene. It binds with two molecules : transforming growth factor alpha and epidermal growth factor, which occur when tissues are inflamed by cigarette smoke, or some viruses and bacteria.  1, record 4, English, - epidermal%20growth%20factor%20receptor

Record 4,  Textual support,  French

Record number: 4, Textual support number: 1 CONT

[...] anticorps monoclonaux qui ciblent le récepteur du facteur de croissance épidermique (R-EGF) présent à la surface d’une cellule cancéreuse. Le R-EGF envoie des signaux qui favorisent la croissance et la survie des cellules cancéreuses.  1, record 4, French, - r%C3%A9cepteur%20du%20facteur%20de%20croissance%20%C3%A9pidermique

Record 4,  Textual support,  Spanish

Record number: 4, Textual support number: 1 CONT

Muchas células cancerosas tienen una proteína, conocida como receptor del factor de crecimiento epidérmico (EFGR), en su superficie, mientras que las células sanas no expresan esta proteína tan fuertemente. Conjugando, o uniendo las nanopartículas de oro a un anticuerpo contra el EFGR, llamado anti-EFGR, los investigadores pueden lograr que se unan a las células cancerígenas.  1, record 4, Spanish, - receptor%20de%20factor%20de%20crecimiento%20epid%C3%A9rmico

Record number: 4, Textual support number: 1 OBS

EFGR por sus siglas en inglés.  2, record 4, Spanish, - receptor%20de%20factor%20de%20crecimiento%20epid%C3%A9rmico

Record number: 4, Textual support number: 2 OBS

Ficha realizada en colaboración con los estudiantes del Certificado en Traducción español-inglés del Glendon College, York University, Toronto, Canada.  2, record 4, Spanish, - receptor%20de%20factor%20de%20crecimiento%20epid%C3%A9rmico

Record 5,  Textual support,  English

Record number: 5, Textual support number: 1 DEF

[An enzyme] mediating the degradation of the extracellular matrix, cartilage formation, the release of tumor necrosis factor alpha, a cytokine involved in inflammatory reactions, in embryogenesis, cell migration, etc.  1, record 5, English, - metalloproteinase

Record 5,  Textual support,  French

Record number: 5, Textual support number: 1 DEF

Protéase ayant pour cofacteur un métal.  1, record 5, French, - m%C3%A9talloprot%C3%A9inase

Record number: 5, Textual support number: 1 CONT

Parmi les métalloprotéases, on trouve des carboxypeptidases à zinc, des aminopeptidases à manganèse ou magnésium, des dipeptidases dont l'activité nécessite du zinc, du manganèse ou du cobalt, etc.  1, record 5, French, - m%C3%A9talloprot%C3%A9inase

Record 5,  Textual support,  Spanish

Record 6,  Textual support,  English

Record number: 6, Textual support number: 1 DEF

The variety of interferon that is produced by sensitized T lymphocytes on stimulation by specific antigens.  1, record 6, English, - gamma%20interferon

Record number: 6, Textual support number: 1 OBS

Besides its action in preventing viral replication, it is a macrophage-activating factor. It is structurally quite distinct from the classical interferons(alpha interferon and Beta interferon).  1, record 6, English, - gamma%20interferon

Record 6,  Textual support,  French

Record number: 6, Textual support number: 1 DEF

Cytokine produite par les lymphocytes T, et les cellules NK et qui induit l'expression des molécules de classe II du CMH, la différenciation des monocytes en macrophages et l'activation de leurs différentes propriétés.  1, record 6, French, - interf%C3%A9ron%20gamma

Record 6,  Textual support,  Spanish

Record number: 6, Textual support number: 1 OBS

Secretado por células T [como] reacción ante un antígeno, suprime la reproducción viral y actúa como linfocina, estimulando a los monocitos, macrófagos y otras células del sistema inmune.  1, record 6, Spanish, - interfer%C3%B3n%20gamma

Record 7,  Textual support,  English

Record number: 7, Textual support number: 1 CONT

Surgical biopsies from 10 head and neck squamous cell carcinomas were labeled in vitro with bromodeoxyuridine. In histological sections, bromodeoxyuridine-positive nuclei and beta-fibroblast growth factor(beta-FGF) were stained using immunohistochemistry. In clearly discernible clusters of tumor cells, the cytoplasm shows strong positive beta-FGF staining, whereas other tumor regions are completely beta-FGF negative... Three classes of mesoderm-inducing factor(MIF) that might be responsible for... interaction in vivo... These are members of the transforming growth factor type beta(TGF-beta), fibroblast growth factor(FGF) and Wnt families... Six well-characterized human growth factors were chosen for detailed investigation by topical application to standardized skin wounds in swine : epidermal growth factor(EGF), transforming growth factors alpha and beta(TGF-alpha and TGF-beta), fibroblast growth factor(FGF), insulin-like growth factor-1(IGF-l), and platelet-derived growth factor(PDGf). [Source : PASCAL database].  1, record 7, English, - beta%20fibroblast%20growth%20factor

Record 7,  Textual support,  French

Record number: 7, Textual support number: 1 OBS

Source : base de données PASCAL.  1, record 7, French, - facteur%20de%20croissance%20du%20fibroblaste%20b%C3%AAta

Record 7,  Textual support,  Spanish

Record 8,  Textual support,  English

Record number: 8, Textual support number: 1 CONT

Transforming growth factor alpha in arterioles : cell surface processing of its precursor by elastases.  3, record 8, English, - transforming%20growth%20factor%20alpha

Record number: 8, Textual support number: 1 OBS

Tiré de: Molecular and cellular biology, 1990, 10 (9), 4596-4602.  3, record 8, English, - transforming%20growth%20factor%20alpha

Record 8,  Textual support,  French

Record number: 8, Textual support number: 1 CONT

Le TGF a qui présente une forte homologie avec l'epidermal growth factor stimule l'angiogénèse in vivo et est mitogène pour les cellules endothéliales. Le TGF B entraîne in vivo, après injection sous-cutanée, une accumulation de macrophages, de fibroblastes et de collagène; et induit une néovascularisation. En revanche, in vitro, il inhibe la croissance des cellules endothéliales. Son activité angiogénique in vivo met donc probablement en jeu les macrophages.  2, record 8, French, - facteur%20de%20croissance%20transformant%20alpha

Record 8,  Textual support,  Spanish

Record 9,  Textual support,  English

Record number: 9, Textual support number: 1 CONT

... all manufacturers were pulling away from the dry heat-treatment method of fractionation, and almost all products produced in the USA would be wet heat-treated. He referred to the Factor VIII produced by Armour, under the name "Monoclonate", which is made from monoclonal antibody, then purified and washed to eliminate viral agents and various proteins, and finally dry heat-treated.... Based on the latest information available... Cutter uses a dry heat process, Alpha uses a wet heat process, and Armour is involved in a monoclonal short heat process.  1, record 9, English, - monoclonal%20short%20heat%20process

Record 9,  Textual support,  French

Record number: 9, Textual support number: 1 OBS

Sous-domaine : fractionnement du sang.  2, record 9, French, - proc%C3%A9d%C3%A9%20de%20fractionnement%20combinant%20les%20anticorps%20monoclonaux%20et%20la%20chaleur%20de%20courte%20dur%C3%A9e

Record number: 9, Textual support number: 2 OBS

Procédé utilisé pour purifier le facteur VIII, (Composé du sang, administré aux hémophiles) de toutes les impuretés mais principalement d'agents viraux tel le virus du SIDA.  1, record 9, French, - proc%C3%A9d%C3%A9%20de%20fractionnement%20combinant%20les%20anticorps%20monoclonaux%20et%20la%20chaleur%20de%20courte%20dur%C3%A9e

Record 9,  Textual support,  Spanish