TERMIUM Plus®

The Government of Canada’s terminology and linguistic data bank.

MTDNA [4 records]

Record 1 2012-03-01

English

Subject field(s)
  • Genetics

French

Domaine(s)
  • Génétique
DEF

ADN constituant le génome des mitochondries. [Définition normalisée par l’AFNOR et reproduite avec son autorisation.]

OBS

ADN mitochondrial; ADNmt : terme et abréviation normalisés par l’AFNOR.

Spanish

Campo(s) temático(s)
  • Genética
CONT

Se abordó el examen del ADN mitocondrial (que codifica una docena de proteínas que la mitocondria necesita para su funcionamiento), en parte, porque se había visto que la capacidad de los orgánulos para generar energía declinaba con la edad.

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Record 2 2010-04-13

English

Subject field(s)
  • Genetics
CONT

McShane MA, Hammans SR, Sweeney M, Holt IJ et al. Pearson syndrome and mitochondrial encephalomyopathy in a patient with a deletion of mtDNA. Am J, Hum Genet 48 : 39(1991) Abstract.

French

Domaine(s)
  • Génétique
DEF

Pancytopénie de la première enfance avec insuffisance pancréatique.

Spanish

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Record 3 1999-05-04

English

Subject field(s)
  • Genetics
OBS

The transcription is occurring in opposite directions and starting form a single point.

CONT

We have mapped the major cis-acting elements required for transcription and replication of mtDNA. Mitochondrial RNA polymerase and a 40-kDa factor are required to initiate transcription form promoters that consist of matches to a simple decanucleotide consensus sequence, ACPuTTATA. Binding of a tetramer of an abundant HMG-box containing factor, mtTFA, to a single site stimulates divergent transcription from clustered mitochondrial promoters. We are studying the control of synthesis of these proteins as well as the mechanisms by which they interact at promoters.

French

Domaine(s)
  • Génétique

Spanish

Save record 3

Record 4 1998-12-02

English

Subject field(s)
  • Cytology
  • Genetics
CONT

The introduction of normal mtDNA via cytoplasts into the heteroplasmic cell is effective, as shown by the production of fusion proteins. The formation of fusion proteins of deleted mtRNA transcribed from deleted mtDNA in heteroplasmic cells indicated intermitochondrial communication, because the deletion resulted in the lack of several tRNAs.

French

Domaine(s)
  • Cytologie
  • Génétique
CONT

De plus, les divers ovocytes d'une femme qui a des cellules hétéroplasmiques ont des proportions variables d'ADN mitochondrial muté; ses enfants n'ont pas le même nombre de molécules d'ADN mitochondrial muté ni la même répartition de ces molécules dans les tissus; la nature et la gravité de leurs symptômes différeront.

Spanish

Save record 4

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