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PEPTIDE OBTENU SYNTHESE NON RIBOSOMIQUE [1 record]

Record 1 2012-10-25

English

Subject field(s)
  • Biotechnology
  • Immunology
DEF

A large class of medically and biologically important secondary metabolites produced by bacteria and fungi.

CONT

Cyclic peptides (more generally and correctly known as non-ribosomally synthesized peptides or NRPs) are an important and widespread class of secondary metabolites. Many of them are biologically active and well-known for their medical and pharmaceutical properties. For example, penicillin, amatoxins from poisonous mushrooms, and the immunosuppressant cyclosporin are all non-ribosomally synthesized peptides. All NRPs are biosynthesized by a family of functionally and structurally related enzymes known as non-ribosomal peptide synthetases (NRPSs).

French

Domaine(s)
  • Biotechnologie
  • Immunologie
OBS

La synthèse est essentiellement due à des gènes comprenant ceux des polykétides synthases et des peptides synthases (synthèse non ribosomique de peptides).

OBS

peptide produit par synthèse non ribosomique : expression proposée par analogie avec «peptide produit par synthèse ribosomique».

Spanish

Campo(s) temático(s)
  • Biotecnología
  • Inmunología
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